NIHR Leeds Clinical Research Facility carries out high quality early stage and experimental clinical trials to help new treatments and tests reach patients more quickly.

Our core funding comes from the National Institute for Health Research (NIHR) and we work with industry, research councils and charities to run over 100 early stage, experimental or complex trials each year. We provide a welcoming, professional and safe environment for patients taking part in our trials, supported by clinical services within Leeds Teaching Hospitals. Patients and the public play a key role in our research, not only as participants, but also helping us in shaping the direction of our work and in the design of research initiated in Leeds. Our work includes a wide range of disease specialties, including research in paediatrics, neuroscience and gastroenterology, but we have particular expertise and a strong track-record in the following areas:

Cardiovascular research: heart failure and coronary disease, 
Musculoskeletal research: conditions such as arthritis and rheumatism,
Oncology research: cancers that involve solid tumour, 
Haematology research:  including cancers of the blood 
Oral and dental health: conditions affecting the mouth and teeth
Paediatrics: diseases in children

Leeds Clinical Research Facility logo outlined RGB COL


With our experienced team and excellent facilities, we have the skills and capacity to run all types of high-quality complex trials across the majority of disease areas. We are part of a world class medical and clinical research base at one of the largest NHS Trusts in the country, which provides specialist care to over five million people.


Our welcoming, high-spec in-patient and out-patient units, dedicated for clinical trials, incorporate state-of-the-art equipment, particularly in imaging and diagnostics, and are located close to specialised research laboratories and nearby clinical services.


Research with the CRF mainly focuses on the early stages of testing new treatments, new techniques or new medical devices, to enable patients to benefit from these advances as quickly as possible. We also run later stage trials, where these require the use of complex or experimental techniques, procedures and monitoring.