Leeds General Infirmary CRF (LGI CRF)

The Leeds General Infirmary CRF (LGI CRF) was estabilished in 2014 and located within the Yorkshire Heart Centre. This CRF has a specialist focus on cardiovascular and neuroscience research with easy access to:

•             Clinical Trials Pharmacy: 24 hour access/pharmacy staff/aseptic suite.

•             ICU and HDU: 24/7 specialist critical care outreach (transfer time <5 minutes).

•             Coronary Care Unit: acute cardiology wards/out-patients/cardiothoracic/neurosurgical theatres.

•             Six Cardiac Catheter laboratories (2 with research facilities/software) for experimental medicine trials (STEMI/stem cell therapies, stenting, structural heart interventions).

•             Leeds Cardiac Magnetic Resonance Imaging Service : 3 state-of-the-art 1.5T/3T MRI scanners.

•             Advanced Imaging Centre (MRC National Centre for Hyperpolarised MRI): 1H/31P MR Spectroscopy, quantitative perfusion imaging, Diffusion Tensor Imaging, Parametric mapping and 4-dimensional flow capabilities.

•             Centre for Translational Cardiovascular Imaging (University of Leeds):  Part of the Leeds Multidisciplinary Cardiovascular Research Centre (British Heart Foundation).

  • Leeds Teaching Hospitals Pathology Department: Clinical Genetics (including research),Microbiology, Cellular Pathology, Blood Transfusion Services, Blood Sciences, Digital Pathology, Genetics Lab, Specialist Laboratory Medicine (SLM), Solid Malignancy Diagnostic Service (SMDS).

 Onsite Clinical Resources:

•             Clinical bay (4 treatment beds/chairs): outpatient/day-care, overnight stays, cardio-pulmonary assessment area.

•             Two clinical consultation/examination rooms.

•             Patient discussion and consent room.

•             Sample preparation/storage laboratory.

•              Laboratory Freezers:  -20oC  x 1 (monitored with calibrated laboratory digital thermometer)

•              Laboratory Sample Fridge x 1 (monitored with calibrated laboratory digital thermometer)

•              Bench Top Ambient Centrifuge: Up to 15,000 rpm (fixed and swing angle) x 1

•             Portable Vital Signs Monitors (2), Emergency Resuscitation Trolley (1), Urine Analyser Machine (1), 12 Lead Portable ECG Machine (2), Blood Glucose Monitor (1), Volumetric Infusion Pumps (1), Audio Visual Facilities,

•             Exercise physiology laboratory/respiratory gas analysis area: Integrated Cardiopulmonary Exercise Testing (CPEX) exercise equipment used to assess the performance of the heart and lungs at rest and during exercise.

  • Upright Bicycle (2), Treadmill (1), Recumbent Bicycle (1)
  • Cardiac Monitoring
  • Pacemaker Programmers (4)

•             Ultrasound imaging rooms: 4D Echocardiograph (3), portable ultrasound machine (1)

•             Clinical physiology measurement room.

•              Dynamometer

•              Microneurography Equipment

  • Haemodynamic Monitor

•             Seminar room.

•             Reception/waiting area.

•             Office.