The Leeds General Infirmary CRF (LGI CRF) was estabilished in 2014 and located within the Yorkshire Heart Centre. This CRF has a specialist focus on cardiovascular and neuroscience research with easy access to:
• Clinical Trials Pharmacy: 24 hour access/pharmacy staff/aseptic suite.
• ICU and HDU: 24/7 specialist critical care outreach (transfer time <5 minutes).
• Coronary Care Unit: acute cardiology wards/out-patients/cardiothoracic/neurosurgical theatres.
• Six Cardiac Catheter laboratories (2 with research facilities/software) for experimental medicine trials (STEMI/stem cell therapies, stenting, structural heart interventions).
• Leeds Cardiac Magnetic Resonance Imaging Service : 3 state-of-the-art 1.5T/3T MRI scanners.
• Advanced Imaging Centre (MRC National Centre for Hyperpolarised MRI): 1H/31P MR Spectroscopy, quantitative perfusion imaging, Diffusion Tensor Imaging, Parametric mapping and 4-dimensional flow capabilities.
• Centre for Translational Cardiovascular Imaging (University of Leeds): Part of the Leeds Multidisciplinary Cardiovascular Research Centre (British Heart Foundation).
- Leeds Teaching Hospitals Pathology Department: Clinical Genetics (including research),Microbiology, Cellular Pathology, Blood Transfusion Services, Blood Sciences, Digital Pathology, Genetics Lab, Specialist Laboratory Medicine (SLM), Solid Malignancy Diagnostic Service (SMDS).
Onsite Clinical Resources:
• Clinical bay (4 treatment beds/chairs): outpatient/day-care, overnight stays, cardio-pulmonary assessment area.
• Two clinical consultation/examination rooms.
• Patient discussion and consent room.
• Sample preparation/storage laboratory.
• Laboratory Freezers: -20oC x 1 (monitored with calibrated laboratory digital thermometer)
• Laboratory Sample Fridge x 1 (monitored with calibrated laboratory digital thermometer)
• Bench Top Ambient Centrifuge: Up to 15,000 rpm (fixed and swing angle) x 1
• Portable Vital Signs Monitors (2), Emergency Resuscitation Trolley (1), Urine Analyser Machine (1), 12 Lead Portable ECG Machine (2), Blood Glucose Monitor (1), Volumetric Infusion Pumps (1), Audio Visual Facilities,
• Exercise physiology laboratory/respiratory gas analysis area: Integrated Cardiopulmonary Exercise Testing (CPEX) exercise equipment used to assess the performance of the heart and lungs at rest and during exercise.
- Upright Bicycle (2), Treadmill (1), Recumbent Bicycle (1)
- Cardiac Monitoring
- Pacemaker Programmers (4)
• Ultrasound imaging rooms: 4D Echocardiograph (3), portable ultrasound machine (1)
• Clinical physiology measurement room.
• Dynamometer
• Microneurography Equipment
- Haemodynamic Monitor
• Seminar room.
• Reception/waiting area.
• Office.